DEVELOPMENT

EASYNOSE®

Specially designed for sino-nasal treatment.

The EASYNOSE is a nebulizer device developed for nasal delivery.

Simply innovative, this nasal nebulization system minimizes penetration of aerosol in the pulmonary area, and increases the nasal and sino-nasal aerosol deposition.
 
  • Really compliant nebulization system
  • No patient participation
     

    In vivo study

    Scintigraphic evaluation of the EASYNOSE nebulizer (B) in healthy volunteers with DTPA-Tc99m aerosol, in comparison with a standard sonic nasal jet-nebulizer (A).
     

AEROSOL DEPOSITIONEASYNOSEJET-NEBULIZER
Nasal cavities 99 +/- 3% 73 +/- 10%
Lungs <1% 27 +/- 10%

 

Referencies

 
- Efficacy of tobramycin aerosol in nasal polyposis. Bonfils P, Escabasse V, Coste A, Gilain L, Louvrier C, Serrano E, de Bonnecaze G, Mortuaire G, Chevalier D, Laccourreye O, Mainardi JL. Eur Ann Otorhinolaryngol Head Neck Dis. 2015 Jun; 132(3): 119-23 Pubmed abstract
 
- Nasal nebulisation of tobramycin: preclinical and clinical study on post-operative suppurations in nasal polyposis patient. Prulière-Escabasse V., Vecellio L., Le Guellec S., Bonfils P. ISAM 2015 Poster PDF file
 
- Validation of Anatomical Models to Study Aerosol Deposition in Human Nasal Cavities. Le Guellec S., Le Pennec D., Gatier S., Leclerc L., Cabrera M., Pourchez J., Diot P., Reychler G., Pitance L., Durand M., Jamar F., Vecellio L. Pharmaceutical Research, 2013 sept. Pubmed abstract
 
- In vivo / in vitro comparison of aerosol deposition in nasal cavities. Le Guellec S., Le Pennec D., Gatier S., Leclerc L., Cabrera M., Pourchez J., Diot P., Reychler G., Pitance L., Durand M., Jamar F., Vecellio L. ISAM 2013 Poster PDF file
 
- In vivo/in vitro comparison of aerosol nasal deposition. Le Guellec S., Le Pennec D., Durand M., Pourchez J, Jamar J., Chantrel G., Vecellio L. Oral presentation, DDL 23, 2012 Summary PDF file

- Scintigraphy evaluation of the Easynose nasal nebulizer in a nasal cast model. Le Guellec S., Gatier S., Le Pennec D., Vullo F., Chantrel G., Vecellio L. DDL22, 2011 and ERS 24th/ ISIAN 31st 2012 Poster PDF file
 
- Deposition of aerosols delivered by nasal route with jet and mesh nebulizers. Vecellio L., De Gersem R., Le Guellec S., Reychler G., Pitance L., Le Pennec D., Diot P., Chantrel G., Bonfils P., Jamar F. Int J Pharm. 2011 Apr 4; 407(1-2): 87-94 Pubmed abstract
 
- Deposition of aerosols delivered by nasal route with jet and mesh nebulizers. Vecellio L., De Gersem R., Le Guellec S., Reychler G., Pitance L., Le Pennec D., Diot P., Chantrel G., Bonfils P., Jamar F.
DDL21, 2010 with abstract available on JAM, 2011, 24(6): 313-314 Poster PDF file
 
- A new prototype nebulizer to optimize aerosol deposition into maxillary sinus and to limit lung deposition. Le Guellec S., Dubois F., Chantrel G., Charrouin L., Gatier S., Vecellio L. RDD, 2009 Poster PDF file
 
Aerodrug, Faculté de Médecine, Bâtiment M, 10 ter boulevard Tonnellé, 37032 TOURS France.